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Required Resources: I will include some part of the reading so you can cite from that and also an outside scholarly source.
Read/review the following resources for this activity:
Textbook: Chapter 9
Lesson 7 Reading
Minimum of 1 scholarly source AND one appropriate resource such as the textbook, math video and/or math website
In your reference for this assignment, be sure to include both your text/class materials AND your outside reading(s).
Initial Post Instructions: At the bottom of Chapter 9 is your reference.
Describe a hypothesis test study that would help your work or conclusions in some way. Describe what variable would be tested and what would be your guess of the value of that variable. Then include how the result, if the null were rejected or not, might change your conclusions or actions in some way. Here is a class mates discussion.
A hypothesis test study that I have seen develop and used a lot in my work in the (NICU) Neonatal Intensive Care Unit is the use of surfactant to help our population breathe easier and be better oxygenated.
Before the 90s, there wasn’t a lot that we could do to help infants oxygenate effectively because of decreased surfactant in their lungs.Their alveoli would close down with exhalation and without the lubrication from the surfactant it was too much work for them to “pop” the back open so that exchange would take place. The first effect it was made from bovine lung tissue. With many, many studies, they now make it from Cow, pig, and artificial surfactants. This is made it possible for us help lubricate our infants alveoli so that when they exhale it collapses, it doesn’t stick but it lubricated and when they inhale is able to easily pop open, so gas exchange can take place. Without this many infants today would not be here or would have worse chronic lung conditions. So 95% of 865 survivors (Approx. 822) infants needed supplemental oxygen.(Marshall,D.D. et al,1999)Among 865 survivors to 36 weeks’ postmenstrual age, 224 (26%) had CLD. Nosocomial infection (OR: 2.0; 95% CI: 1.4–3.3), fluid intake on day 2 (OR: 1.06 per 10 mL increase; 95% CI: 1.01–1.11), and the need for ventilation at 48 hours of life (OR: 2.2; 95% CI: 1.3–3.7) were associated with an increased risk of CLD. Among infants ventilated at 48 hours, nosocomial infection (OR: 1.64; 95% CI: 1.02–2.62) and PDA (OR: 1.9; 95% CI: 1.2–3.1) were associated with an increased risk.
there are many ongoing testing going on in my facility at present. We are doing blind studies on infants below 32 weeks or 2000 grams. There are different brands which have different makeups of surfactant being tested. After all of the results are in we can hopefully tell which type works best in our population.
The Null hypothesis would be no change in oxygenation status
The alternative hypothesis would be reduction on oxygen requirements and decreased ventilation support needed.
The Null would nit be rejected in this case because it would mean that the research supports no advantage of surfactant administration.
Marshall, D. D., Kotelchuck, M., Young, T. E., Bose, C. L., Kruyer, L., O’Shea, T. M., & North Carolina Neonatologists Association. (1999). Risk Factors for Chronic Lung Disease in the Surfactant Era: A North Carolina Population-based Study of Very Low Birth Weight Infants. Pediatrics (Evanston), 104(6), 1345–1350. https://doi.org/10.1542/peds.104.6.1345
Holmes, A., Illowsky, B., & Dean, S. (2017). Introductory business statistics. OpenStax. https://openstax.org/details/books/introductory-business-statistics
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